PE-454609-1 MYOCARDIAL WORK IN VENTRICULAR PREEXCITATION

Ventricular preexcitation alters the electromechanical activation sequence and may induce left ventricular (LV) contractile discoordination pathologic remodelling in selected cases. To evaluate LV myocardial work before after accessory pathway (AP) ablation patients with WPW to compare them normal controls. Mechanical mapping calculation was performed 11 pediatric syndrome/pattern sided or paraseptal APs undergoing catheter (successful 10/11) 8 healthy age-matched controls using speckle tracking echocardiography GE ECHOPAC version 204.57.0.745 software integrated AFI module. An 18-segmental echocardiographic model used. Global efficiency (GWE) calculated as ratio of global constructive sum wasted (GWW). The time from delta wave onset R peak lead V6 (delta R) used quantify degree preexcitation. Before GWW higher (164 vs 102 mmHg%, P=0.015) GWE lower (median 91 94%, P=0.010) After successful decreased 164 93 mmHg% (P=0.006) increased 91.1 94.0 % (P=0.006). tended correlate negatively interval (R=0.59, P=0.056). ablation, segmental WE distance AP insertion median 69.5 at location 98.0 distant segments (P<0.001). equally distributed among (Figure). localized a (IQR) 0 (0-1) EP mapped location. induces significant inefficiency adjacent which correlates is normalized ablation. amount asymptomatic be considered when assessing potential for discussing indication prophylactic localize manifest APs.